Quick answer — My Friend's Little Sister Has It In for Me!: the opening theme is "Uza Kawaikute Nani ga Warui!" and the ending theme is "Hoshi no Kodou".
For high schooler Akiteru Ooboshi, the whole youthful experience thing—like fun, friendships, and even having a girlfriend—is a complete waste of time. So when his best friend’s sister, Iroha Kohinata, keeps teasing him, Akiteru naturally finds it annoying. She practically lives in his room, she’s always on his bed… Produced by BLADE, this comedy, romance, and slice of life series premiered in Fall 2025. The series spans 12 episodes and is currently finished.
Also known as: ImoUza · いもウザ · น้องสาวเพื่อนตัวร้ายกับนายจืดจาง
My Friend's Little Sister Has It In for Me! has 12 episodes and is finished.
My Friend's Little Sister Has It In for Me! was produced by BLADE and released in 2025.
My Friend's Little Sister Has It In for Me! is classified under Comedy, Romance, Slice of Life.
My Friend's Little Sister Has It In for Me! premiered in Fall 2025.
The opening theme of My Friend's Little Sister Has It In for Me! is "Uza Kawaikute Nani ga Warui!".
The ending theme of My Friend's Little Sister Has It In for Me! is "Hoshi no Kodou".
My Friend's Little Sister Has It In for Me! is based on a light novel.
My Friend's Little Sister Has It In for Me! is listed on Crunchyroll. Availability varies by region.
Character data from AniList.
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